3-keto-5β-Abiraterone Chemical Properties

Melting point:

151 - 154oC

Boiling point:

486.0±45.0 °C(Predicted)

Density 

1.094±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer, under Argon

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly), Dichlorome

pka

5.32±0.12(Predicted)

form 

Solid

color 

White to Off-White

3-keto-5β-Abiraterone Usage And Synthesis

Uses

3-keto-5β-Abiraterone is a metabolite of abiraterone (A108490) which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.