6′-O-galloylalbiflorin Chemical Properties

Boiling point:

923.1±65.0 °C(Predicted)

Density 

1.69±0.1 g/cm3(Predicted)

form 

Solid

pka

7.84±0.25(Predicted)

color 

Off-white to light yellow

6′-O-galloylalbiflorin Usage And Synthesis

Uses

Galloylalbiflorin (6′-O-Galloylalbiflorin) is an androgen receptor (AR) antagonist (IC50=53.3 μM) and can be found in the roots of Paeonia lactiflora. Galloylalbiflorin shows anti-androgens activity[1].

Definition

ChEBI: 6'-O-galloylalbiflorin is a monoterpene glycoside that is albiflorin carrying a galloyl substituent at position 6. Isolated from the roots of Paeonia lactiflora. It has a role as a plant metabolite, an androgen antagonist and an antineoplastic agent. It is a beta-D-glucoside, a gamma-lactone, a gallate ester, a bridged compound, a monoterpene glycoside and a secondary alcohol. It is functionally related to an albiflorin.

References

[1] Kazuto Washida, et al. Androgen modulators from the roots of Paeonia lactiflora (paeoniae radix) grown and processed in nara prefecture, Japan. Chem Pharm Bull (Tokyo). 2009 Sep;57(9):971-4. DOI:10.1248/cpb.57.971