3-CHLORO-4-FLUOROTHIOPHENOL Chemical Properties

Boiling point:

70 °C (2 mmHg)

Density 

1.375±0.06 g/cm3 (20 ºC 760 Torr)

refractive index 

1.5705-1.5735

Flash point:

68-70°C/2mm

storage temp. 

2-8°C, stored under nitrogen

solubility 

Sparingly Soluble (0.014 g/L) (25°C).

pka

5.63±0.10(Predicted)

Appearance

Colorless to light yellow Liquid

Sensitive 

Stench

CAS DataBase Reference

60811-23-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

36/37/38-20/21/22-22

Safety Statements 

36/37/39-26

Hazard Note 

Irritant/Stench

HazardClass 

IRRITANT, STENCH

HS Code 

2930909899

MSDS

• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-CHLORO-4-FLUOROTHIOPHENOL Usage And Synthesis

Chemical Properties

clear colorless to light yellow liquid

Uses

Used as pharamaceutical intermediate.

Synthesis

To a solution of 3-chloro-4-fluorophenyl dimethyl thiosulfate (1200 mg, 4.33 mmol) in methanol (15 mL) was added 10% aqueous NaOH (8 mL). The reaction was kept at 50 ??C and stirred for 4 h. TLC analysis showed total consumption of SM. The reaction mixture was cooled to room temperature and pH was adjusted to 3. DCM (15 ml) was then added. The organic layer was evaporated to dryness to give 3-chloro-4-fluorobenzenethiol.

3-CHLORO-4-FLUOROTHIOPHENOL(60811-23-6)Related Product Information

• 3-CHLORO-4-FLUOROTHIOPHENOL
• 5-CHLORO-2,4-DIFLUOROBENZENESULFONYL CHLORIDE
• 3-CHLORO-4-FLUOROBENZENESULFONYL CHLORIDE
• 3-CHLORO-4-FLUOROBENZENESULFONAMIDE
• 2-Chloro-4-fluorothiophenol 97%,2-Chloro-4-fluorothiophenol97%,2-CHLORO-4-FLUOROTHIOPHENOL
• 4-Fluorothiophenol
• 5-CHLORO-2,4-DIFLUOROBENZENESULFONAMIDE
• 4-([(3-CHLORO-4-FLUOROPHENYL)SULFONYL]AMINO)BENZOIC ACID
• N-[(3-CHLORO-4-FLUOROPHENYL)SULFONYL]PHENYLALANINE
• LEUCINE, N-[(3-CHLORO-4-FLUOROPHENYL)SULFONYL]-
• 2-[[(3-CHLORO-4-FLUOROPHENYL)SULFONYL]AMINO]-4-(METHYLTHIO)BUTANOIC ACID
• N-[(3-CHLORO-4-FLUOROPHENYL)SULFONYL]VALINE
• 3-[[(3-CHLORO-4-FLUOROPHENYL)SULFONYL]AMINO]PROPANOIC ACID
• 3-CHLORO-5-FLUOROTHIOPHENOL
• 1-[(3-CHLORO-4-FLUOROPHENYL)SULFONYL]PROLINE
• 4-(([(3-CHLORO-4-FLUOROPHENYL)SULFONYL]AMINO)METHYL)BENZOIC ACID
• 2-([(3-CHLORO-4-FLUOROPHENYL)SULFONYL]AMINO)ACETIC ACID
• RARECHEM AL FA 0031