SULINDAC SULFONE
SULINDAC SULFONE Basic information
- Product Name:
- SULINDAC SULFONE
- Synonyms:
-
- SULINDAC SULFONE
- (Z)-5-FLUORO-2-METHYL-1[P-(METHYLSULFONYL)BENZYLIDENE]INDENE-3-ACETIC ACID
- APTOSYN
- FGN-1
- EXISULIND
- APTOSYN/EXISULIND
- 5-Fluoro-2-methyl-1-[(Z)-4-(methylsulfonyl)benzylidene]-1H-indene-3-acetic acid
- 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfonyl)phenyl)methylene)-, (1Z)-
- CAS:
- 59973-80-7
- MF:
- C20H17FO4S
- MW:
- 372.41
- Product Categories:
-
- Metabolites & Impurities
- Sulfur & Selenium Compounds
- Intermediates & Fine Chemicals
- Metabolites
- Pharmaceuticals
- Mol File:
- 59973-80-7.mol
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SULINDAC SULFONE Chemical Properties
- Melting point:
- 248-250°C
- alpha
- D -62° (c = 1 in CHCl3)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO: >25 mg/mL
- form
- solid
- color
- yellow
- Stability:
- Hygroscopic
MSDS
- Language:English Provider:SigmaAldrich
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SULINDAC SULFONE Usage And Synthesis
Chemical Properties
Yellow Solid
Uses
Sulindac Sulfone is an inhibitor of growth and inducer of apoptosis in cancer cell lines.
Definition
ChEBI: A sulfone metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. It inhibits the development and induces regression of premalignant adenomatous polyps. Lipoxygenase and Cox-2 inhibitor.
SULINDAC SULFONESupplier
J & K SCIENTIFIC LTD.
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Chemsky(shanghai)International Co.,Ltd.
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Beijing HuaMeiHuLiBiological Chemical
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Guangzhou Isun Pharmaceutical Co., Ltd
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