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NARASIN

Basic information Safety Supplier Related

NARASIN Basic information

Product Name:
NARASIN
Synonyms:
  • monteban
  • narasina
  • narasin from streptomyces auriofaciens
  • Narasia A
  • Salinomycin, 4-methyl-, (4S)-
  • (4S)-4-Methylsalinomycin
  • (4S)-4β-Methylsalinomycin
  • Narasin (125 mg)
CAS:
55134-13-9
MF:
C43H72O11
MW:
765.03
EINECS:
213-574-4
Product Categories:
  • Chiral Reagents
  • Heterocycles
  • Antibacterial
  • Antibiotics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Antibiotics A to
  • Antibiotics N-SAntibiotics
  • Interferes with Cell Membrane Permeability (Ionophores)Spectrum of Activity
  • L - Z
  • Mechanism of Action
Mol File:
55134-13-9.mol
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NARASIN Chemical Properties

Melting point:
98-100°
alpha 
D25 -54° (c = 0.2 in methanol)
Boiling point:
842.5±65.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
methanol: soluble20mg/mL
pka
7.9 (80% aq DMF)
form 
solution
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Safety Information

Hazard Codes 
T+
Risk Statements 
28
Safety Statements 
28-36/37-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
VO8640000
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
2941906000
Toxicity
LD50 i.p. in mice: 7.15 mg/kg (Berg)

MSDS

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NARASIN Usage And Synthesis

Chemical Properties

White Solid

Uses

Narasin (4-methylsalinomycin) is a polyether antibiotic isolated from Streptomyces aureofaciens in 1978. Although narasin is a close analogue of salinomycin, the metabolites are produced by different species and are not co-metabolites. Narasin shows broad spectrum activity against Gram positive bacteria including anaerobes and mycoplasma, and also possesses antiviral and limited antifungal activity. Narasin is used in the animal health industry as an in-feed antibiotic and growth promotant.

Uses

Narasin is the main component of a polyether antibiotic complex produced by Streptomyces auriofaciens NRRL 5758 & NRRL 8092. Ionophoric antibiotic which inhibits coccidial infection in poultry and mammals. Coccidiostat; growth stimulant.

Definition

ChEBI: Narasin is a diterpene glycoside.

brand name

Monteban (Lilly).

NARASINSupplier

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