NARASIN Chemical Properties

Melting point:

98-100°

alpha 

D25 -54° (c = 0.2 in methanol)

Boiling point:

842.5±65.0 °C(Predicted)

Density 

1.17±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

methanol: soluble20mg/mL

pka

7.9 (80% aq DMF)

form 

solution

color 

White to off-white

Safety Information

Hazard Codes 

T+

Risk Statements 

28

Safety Statements 

28-36/37-45

RIDADR 

UN 2811 6.1/PG 2

WGK Germany 

3

RTECS 

VO8640000

HazardClass 

6.1(a)

PackingGroup 

II

HS Code 

2941906000

Toxicity

LD50 i.p. in mice: 7.15 mg/kg (Berg)

MSDS

• Language:English Provider:SigmaAldrich

NARASIN Usage And Synthesis

Chemical Properties

White Solid

Uses

Narasin (4-methylsalinomycin) is a polyether antibiotic isolated from Streptomyces aureofaciens in 1978. Although narasin is a close analogue of salinomycin, the metabolites are produced by different species and are not co-metabolites. Narasin shows broad spectrum activity against Gram positive bacteria including anaerobes and mycoplasma, and also possesses antiviral and limited antifungal activity. Narasin is used in the animal health industry as an in-feed antibiotic and growth promotant.

Uses

Narasin is the main component of a polyether antibiotic complex produced by Streptomyces auriofaciens NRRL 5758 & NRRL 8092. Ionophoric antibiotic which inhibits coccidial infection in poultry and mammals. Coccidiostat; growth stimulant.

Definition

ChEBI: Narasin is a diterpene glycoside.

brand name

Monteban (Lilly).

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