1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE Chemical Properties

Melting point:

178 °C

Boiling point:

101.6±50.0 °C(Predicted)

Density 

1.50±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

pka

0.58±0.50(Predicted)

Appearance

White to off-white Solid

BRN 

5811070

CAS DataBase Reference

1481-02-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,T

Risk Statements 

25

Safety Statements 

45

Hazard Note 

Irritant

HS Code 

2933119000

MSDS

• Language:English Provider:ALFA

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE Usage And Synthesis

Synthesis

0.1 mL of methylhydrazine and 10 mL of anhydrous ethanol were added to a 250 mL three-necked flask, stirred and heated to 50°C. Subsequently, 0.1 mol of ethyl trifluoroacetoacetate was slowly added dropwise. After the dropwise addition was completed, the reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, the mixture was cooled to promote crystallization. The resulting yellow solid was collected by vacuum filtration and dried. The yield of the final product was 85.8%.

References

[1] Patent: CN103951663, 2016, B. Location in patent: Paragraph 0091; 0092; 0093
[2] Australian Journal of Chemistry, 2010, vol. 63, # 5, p. 785 - 791

1-METHYL-3-TRIFLUOROMETHYL-2-PYRAZOLIN-5-ONE(1481-02-3)Related Product Information

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