Baceridin Chemical Properties

Boiling point:

1060.2±65.0 °C(Predicted)

Density 

1.074±0.06 g/cm3(Predicted)

pka

13.25±0.70(Predicted)

Sequence

Cyclo(-D-Ala-D-allo-Ile-Val-D-Leu-Leu-Trp)

Baceridin Usage And Synthesis

Uses

Baceridin is a proteasome inhibitor and a cyclic hexapeptide. Baceridin can be isolated from the culture medium of Epiphytic Bacillus. Baceridin can inhibit cell cycle progression and induce tumor cell apoptosis through a p53-independent pathway. Baceridin can be used in cancer research[1].

References

[1] Niggemann J, et al. Baceridin, a cyclic hexapeptide from an epiphytic bacillus strain, inhibits the proteasome. Chembiochem. 2014 May 5;15(7):1021-9. DOI:10.1002/cbic.201300778

Baceridin(1622872-91-6)Related Product Information

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