D,L-ERYTHRO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL
D,L-ERYTHRO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL Basic information
- Product Name:
- D,L-ERYTHRO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL
- Synonyms:
-
- D,L-ERYTHRO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL
- D,L-ERYTHRO-PDMP
- Decanamide, N-[(1R,2S)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-, rel-
- D,L-erythro-PDMP, glucosylceramide synthase inhibitor isomer
- CAS:
- 109760-77-2
- MF:
- C23H38N2O3.ClH
- MW:
- 427.025
- Mol File:
- 109760-77-2.mol
More
Less
D,L-ERYTHRO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL Chemical Properties
- Boiling point:
- 586.0±50.0 °C(Predicted)
- Density
- 1.047±0.06 g/cm3(Predicted)
- pka
- 13.60±0.20(Predicted)
More
Less
D,L-ERYTHRO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL Usage And Synthesis
Uses
D,L-erythro-PDMP is an erythro isomer of PDMP. D,L-erythro-PDMP causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase[1][2].
References
[1] Uemura K, et al. Effect of an inhibitor of glucosylceramide synthesis on cultured rabbit skin fibroblasts. J Biochem. 1990 Oct;108(4):525-30. DOI:10.1093/oxfordjournals.jbchem.a123236
[2] Abe A, et al. Induction of glucosylceramide synthase by synthase inhibitors and ceramide. Biochim Biophys Acta. 1996 Feb 16;1299(3):333-41. DOI:10.1016/0005-2760(95)00217-0