DPO-1
DPO-1 Basic information
- Product Name:
- DPO-1
- Synonyms:
-
- DPO-1
- [1S-(1α,2α,5β)]-[5-Methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphineoxide
- (+)-Neomenthyl diphenylphosphine oxide
- (1S,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl]diphenyl-phosphine oxide
- DOP-1 (Diphenyl phosphine oxide-1)
- Phosphine oxide, [(1S,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]diphenyl-
- inhibit,DPO1,Inhibitor,DPO 1,Potassium Channel,DPO-1,KcsA
- {[(1S,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl](phenyl)phosphoroso}benzene
- CAS:
- 43077-30-1
- MF:
- C22H29OP
- MW:
- 340.44
- Mol File:
- 43077-30-1.mol
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DPO-1 Chemical Properties
- storage temp.
- Store at +4°C
- solubility
- DMSO: soluble2mg/mL, clear (warmed)
- form
- needles
- color
- white
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DPO-1 Usage And Synthesis
Definition
ChEBI: [[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene is a monoterpenoid.
Biological Activity
Blocker of I Kur ultrarapid delayed rectifier potassium current and K V 1.5 channels (IC 50 = 0.31 μ M for rK V 1.5). Displays selectivity for inhibition of I Kur over I to (8-fold), I K1 , I Kr and I Ks (20-fold) in native myocytes and selectivity for rat recombinant K V 1.5 over K V 3.1 (~ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia.
storage
Store at +4°C
DPO-1Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- meilunui@163.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
Shanghai Chiral bio-compound co., Ltd.
- Tel
- 021-5068 3667/17749785980/1029026415; 17749785980
- 1029026415@qq.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com