2, 7-dihydroxy-4, 6-dimethoxy phenanthrene Chemical Properties

Boiling point:

529.0±45.0 °C(Predicted)

Density 

1.334±0.06 g/cm3(Predicted)

pka

9.29±0.30(Predicted)

2, 7-dihydroxy-4, 6-dimethoxy phenanthrene Usage And Synthesis

Uses

3,5-Dimethoxy-2,7-phenanthrenediol (compound 2) is a phenanthrene compound isolated from the roots of Combretum laxum. 3,5-Dimethoxy-2,7-phenanthrenediol is cytotoxic to human cancer cell lines 786-0, MCF-7 and NCI/ADR-RES, with IC50s of 73.26 μM, 118.40 μM and 83.99 μM respectively. 3,5-Dimethoxy-2,7-phenanthrenediol also has free radical scavenging activity with an IC50 of 20.4 μM[1].

Definition

ChEBI: 3,5-Dimethoxy-2,7-phenanthrenediol is a phenanthrol.

References

[1] Bisoli E, et al. Cytotoxic Phenanthrene, Dihydrophenanthrene, and Dihydrostilbene Derivatives and Other Aromatic Compounds from Combretum laxum. Molecules. 2020 Jul 10;25(14):3154. DOI:10.3390/molecules25143154