6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide
6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Basic information
- Product Name:
- 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide
- Synonyms:
-
- 6-Chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide
- (±)-SKF 82526 HydrobroMide
- 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol HydrobroMide
- SKF 82526 HydrobroMide
- 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide
- FENOLDOPAM MONOHYDROBROMIDE
- 6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1h-3-benzazepine-7,8-diol monohydrobromide
- FenoldopaM HydrobroMide
- CAS:
- 67287-54-1
- MF:
- C16H16ClNO3.BrH
- MW:
- 386.67
- EINECS:
- 266-634-7
- Product Categories:
-
- Agonists
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Neurochemicals
- Pharmaceuticals
- Mol File:
- 67287-54-1.mol
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6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Chemical Properties
- Melting point:
- >233°C (dec.)
- storage temp.
- 2-8°C
- solubility
- DMSO: >12mg/mL
- form
- Solid
- color
- off-white
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36-42/43
- Safety Statements
- 22-26-36/37/39
- WGK Germany
- 3
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6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromide Usage And Synthesis
Uses
Dopamine D1-receptor agonist. Antihypertensive.
Uses
Fenoldopam Monohydrobromide is a potent D-1 dopamine agonists.
Biochem/physiol Actions
Fenoldopam is a selective dopamine agonist that is being considered for the parenteral treatment of systemic hypertension. In both an oral and parenteral form, fenoldopam causes peripheral vasodilation by stimulating dopamine-1 adrenergic receptors. Intravenous fenoldopam may provide advantages over sodium nitroprusside because it can induce both a diuresis and natriuresis, is not light sensitive, and is not associated with cyanide toxicity. There is no evidence for rebound hypertension after discontinuation of fenoldopam infusion.
6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-hydroxyphenyl)-1H-3-benzazepinium bromideSupplier
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