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(6R-trans)-3-(hydroxymethyl)-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Basic information Safety Supplier Related

(6R-trans)-3-(hydroxymethyl)-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Basic information

Product Name:
(6R-trans)-3-(hydroxymethyl)-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms:
  • (6R-trans)-3-(hydroxymethyl)-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Deacetylcephalothin
  • Des-acetyl Cephalothin
  • (6R)-3-(Hydroxymethyl)-8-oxo-7α-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (7R)-3-(Hydroxymethyl)-7β-(2-thienylacetylamino)cepham-3-ene-4-carboxylic acid
  • (7R)-3-(Hydroxymethyl)-7β-[(2-thienyl)acetylamino]cepham-3-ene-4-carboxylic acid
  • Cefalonium Impurity B
  • (7R)-3-(hydroxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS:
5935-65-9
MF:
C14H14N2O5S2
MW:
354.4
EINECS:
227-690-8
Mol File:
5935-65-9.mol
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(6R-trans)-3-(hydroxymethyl)-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical Properties

Melting point:
>132°C (dec.)
storage temp. 
-20°C Freezer
solubility 
Dioxane (Very Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Pale Brown
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(6R-trans)-3-(hydroxymethyl)-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Usage And Synthesis

Uses

Deacetylcephalothin (Cefalotin EP Impurity B) is an intermediate and the free acid analogue of Deacetylcephalothin Sodium Salt (D198210), which is an impurity in the synthesis of Cefalonium (C236800) and an analog of Cephalothin (C261150) a first-generation cephalosporin antibiotic used as a long-acting intramammary cerate for infusion of dairy cows.

(6R-trans)-3-(hydroxymethyl)-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidSupplier

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