N6-Benzoyl-5’-O-MMTr-2’-O-methyladenosine 3’-CED phosphoramidite Chemical Properties

pka

8.80±0.10(Predicted)

N6-Benzoyl-5’-O-MMTr-2’-O-methyladenosine 3’-CED phosphoramidite Usage And Synthesis

Uses

MMT-2'-O-Methyl adenosine (n-bz) CED phosphoramidite (compound 1) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies[1].

References

[1] Senthilvelan A, et al. Efficient and Improved Solution-Phase Synthesis of Modified RNA Dinucleotides: Versatile Synthons in Cap 1 mRNA Therapeutics[J]. Organic Process Research & Development, 2022, 26(9): 2771-2778.

N6-Benzoyl-5’-O-MMTr-2’-O-methyladenosine 3’-CED phosphoramidite(2645354-88-5)Related Product Information

• 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine
• N6-BENZOYL-3'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE
• N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine
• 3'-DA CEP
• (N6-BENZOYL)-5'-O-[(N,N-DIISOPROPYLAMINO)-(2-CYANOETHOXY)PHOSPHINYL]-3'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE
• 3-DEAZA-DA CEP
• 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
• 5'-O-FDMT-N6-BENZOYL-2'-DEOXYADENOSINE CEP