8-Mercaptoquinoline Hydrochloride
8-Mercaptoquinoline Hydrochloride Basic information
- Product Name:
- 8-Mercaptoquinoline Hydrochloride
- Synonyms:
-
- Thiooxine
- 8-MERCAPTOQUINOLINE
- 8-Quinolinethiol
- 8-Metcaptoquinoline
- 8-Quinolylmercaptan
- Quinoline-8-thiol
- Thiooxin
- Aids110552
- CAS:
- 491-33-8
- MF:
- C9H7NS
- MW:
- 161.22
- Mol File:
- 491-33-8.mol
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8-Mercaptoquinoline Hydrochloride Usage And Synthesis
Uses
Quinoline-8-thiol is used as a reactant in the preparation of classical and nonclassical 6-arylthio-2,4-diamino-5-ethylpyrrolo[2,3-d]pyrimidines as antifolates and as antitumor agents.
Purification Methods
It is more convenient to make 8-mercaptoquinoline by reduction of the disulfide. [Nakamura & Sekido Talanta 17 515 1970.] The hydrochloride (see thiooxine hydrochloride below) is more stable. [Beilstein 21 III/IV 1197, 21/3 V 30.]
8-Mercaptoquinoline Hydrochloride Preparation Products And Raw materials
Raw materials
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