Basic information Safety Supplier Related

N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE

Basic information Safety Supplier Related

N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE Basic information

Product Name:
N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE
Synonyms:
  • N-BUTYL-N-(4-HYDROXYBUTYL)NITROSAMIN
  • N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE
  • N-BUTYL-N-(4-HYDROXYBUTYL)NITROSAMINE
  • N-BUTYL-N-NITROSO-4-AMINOBUTANOL
  • N-BUTYL-N-BUTAN-4-OL-NITROSAMINE
  • N-BUTYL-N-BUTANOLNITROSAMINE
  • 1-Butanol, 4-(butylnitrosamino)-
  • 4-(1-Butyl-2-oxohydrazino)-1-butanol
CAS:
3817-11-6
MF:
C8H18N2O2
MW:
174.24
EINECS:
625-015-5
Mol File:
3817-11-6.mol
More
Less

N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE Chemical Properties

Boiling point:
167 °C / 5mmHg
Density 
1.01
refractive index 
1.4700-1.4740
Flash point:
147 °C
storage temp. 
2-8°C
form 
clear liquid
pka
15.03±0.10(Predicted)
color 
Light yellow to Amber to Dark green
Stability:
Stability
EPA Substance Registry System
4-(Butylnitrosoamino)butanol (3817-11-6)
More
Less

Safety Information

Hazard Codes 
T
Risk Statements 
45-22
Safety Statements 
53
WGK Germany 
3
RTECS 
EL1225000
HS Code 
2929.90.5090
More
Less

N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE Usage And Synthesis

Chemical Properties

red liquid

Uses

N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN), a carcinogen, is used to induce histiologically relevant aggressive urinary bladder cancer in animal models.

Definition

ChEBI: A nitrosamine that has butyl and 4-hydroxybutyl substituents. In mice, it causes high-grade, invasive cancers in the urinary bladder, but not in any other tissues.

General Description

Dark red liquid.

Air & Water Reactions

Water soluble.

Reactivity Profile

A hydroxylated and nitrated amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Biochem/physiol Actions

Carcinogen used to induce urinary bladder cancer in animal models. The result of exposure is histologically comparable to human urinary bladder tumorigenesis. Used in chemopreventative studies.

N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINESupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Email
market03@meryer.com
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Email
Sales-CN@TCIchemicals.com
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Email
bin.wu@shlschem.com
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611