1,2-BIS(10,12-TRICOSADIYNOYL)-SN-GLYCERO-3-PHOSPHOETHANOLAMINE Chemical Properties

Boiling point:

887.6±75.0 °C(Predicted)

Density 

1.027±0.06 g/cm3(Predicted)

storage temp. 

-20°C

pka

1.17±0.50(Predicted)

form 

powder

1,2-BIS(10,12-TRICOSADIYNOYL)-SN-GLYCERO-3-PHOSPHOETHANOLAMINE Usage And Synthesis

Description

23:2 Diyne PE is a biocompatible and fluorescent molecule composed of two quinoline derivatives and used as a diagnostic tool for cancer. Hydrogen atoms on the rings of the quinoline derivatives are replaced by deuterium atoms which gives it high resistance to light exposure and particle bombardment. It is also a biomimetic molcule because it has been shown to only bind to collagen and cancer cells.

Uses

23:2 Diyne PE [DC(8,9)PE] is a phospholipase-mediated hydrolyzed phosphocoline with palmitic acid (16:0) and Pentacosa-10,12-diynoic acid for tails.

References

[1] Juliano R L, et al. Liposomes as a drug delivery system for antisense oligonucleotides[J]. Antisense research and development, 1992, 2(2): 165-176. DOI:10.1089/ard.1992.2.165