Butadiazamide
Butadiazamide Basic information
- Product Name:
- Butadiazamide
- Synonyms:
-
- Butadiazamide
- N-(5-Butyl-1,3,4-thiadiazol-2-yl)-p-chlorobenzenesulfonamide
- CAS:
- 7007-88-7
- MW:
- 0
- Mol File:
- 7007-88-7.mol
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Butadiazamide Usage And Synthesis
Originator
Butadiazamide,Onbio Inc.
Manufacturing Process
15.7 g of 5-amino-2-n-butyl-1:3:4-thiadiazole (0.1 mol) was dissolved in 150 ml dry pyridine and treated with 21.1 g of ρ-chlorobenzene sulfonyl chloride (0.1 mol). The mixture was heated on a steam bath for 4 h and the pyridine removed by distillation under reduced pressure. The residue was treated with 50 ml 2 N hydrochloric acid, and after filtration the 2-n-butyl-5-ρ- chlorobenzenesulfonamido-1:3:4-thiadiazole as colourless prisms, melting point 129-130°C (recrystallised from benzene) was obtained.
Therapeutic Function
Oral hypoglycemic