gastrin releasing peptide (14-27)
gastrin releasing peptide (14-27) Basic information
- Product Name:
- gastrin releasing peptide (14-27)
- Synonyms:
-
- Bombesin, 1-L-methionine-2-L-tyrosine-3-L-proline-4-L-arginine-7-L-histidine-, (2S-(2alpha,5alpha,6beta(S*)))-
- C-Terminal peptide bombesin
- Grp (14-27)
- L-Methioninamide, L-methionyl-L-tyrosyl-L-prolyl-L-arginylglycyl-L-asparaginyl-L-histidyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-
- 14-27-Porcine gastrin-releasing peptide
- Gastrin Releasing Peptide (14-27), porcine, humam, dog
- CAS:
- 81608-29-9
- MF:
- C75H110N24O16S2
- MW:
- 1667.96
- Mol File:
- 81608-29-9.mol
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gastrin releasing peptide (14-27) Chemical Properties
- Density
- 1.49±0.1 g/cm3(Predicted)
- pka
- 9.84±0.15(Predicted)
- Sequence
- Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2
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gastrin releasing peptide (14-27) Usage And Synthesis
Uses
GRP (14-27) (human, porcine, canine) is a bombesin receptor ligand. The specific binding of GRP (14-27) is inhibited by GTP and GDP, whereas GMP was without effect[1].
References
[1] J B Fischer, et al. The bombesin receptor is coupled to a guanine nucleotide-binding protein which is insensitive to pertussis and cholera toxins. J Biol Chem. 1988 Feb 25;263(6):2808-16. PMID:2830264
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