ChemicalBook > Product Catalog > Biochemical Engineering > Biochemical Reagents > Antibiotic > epidermin
epidermin
epidermin Basic information
- Product Name:
- epidermin
- Synonyms:
-
- epidermin
- PubChem ID: 16132391
- L-Cysteinamide, L-isoleucyl-L-alanyl-D-cysteinyl-L-lysyl-L-phenylalanyl-L-isoleucyl-L-cysteinyl-(2S,3S)-2-amino-3-mercaptobutanoyl-L-prolylglycyl-L-cysteinyl-L-alanyl-L-lysyl-(2Z)-2-amino-2-butenoylglycyl-D-cysteinyl-L-phenylalanyl-L-asparaginyl-D-cysteinyl-L-tyrosyl-N-[(1Z)-2-mercaptoethenyl]-, cyc...
- L-Cysteinamide, L-isoleucyl-L-alanyl-D-cysteinyl-L-lysyl-L-phenylalanyl-L-isoleucyl-L-cysteinyl-(2S,3S)-2-amino-3-mercaptobutanoyl-L-prolylglycyl-L-cysteinyl-L-alanyl-L-lysyl-(2Z)-2-amino-2-butenoylglycyl-D-cysteinyl-L-phenylalanyl-L-asparaginyl-D-cysteinyl-L-tyrosyl-N-[(1Z)-2-mercaptoethenyl]-, cyclic (3→7),(8→11),(16→21),(19→21)-tetrakis(thioether)
- CAS:
- 99165-17-0
- MF:
- C98H141N25O23S4
- MW:
- 2165.59
- Mol File:
- 99165-17-0.mol
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epidermin Chemical Properties
- Density
- 1.41±0.1 g/cm3(Predicted)
- pka
- 9.89±0.15(Predicted)
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epidermin Usage And Synthesis
Description
Epidermin is defined as a lantibiotic produced by S. epidermidis, which is a thioether amino acid–containing antimicrobial peptide active against various bacteria, contributing to bacterial interference and colonization on human skin.
Synthesis
Solid-phase peptide synthesis of epidermin:epidermin is synthesized in the ribosome via a precursor protein, followed by enzymatic modifications. It was isolated from the culture filtrate of Staphylococcus epidermidis TU 3298 by adsorption on Amberlite XAD-8. The basic heneicosapeptide amide was chromatographed on Sephadex LH-20 and purified to homogeneity via multiplicative counter-current distributions in one acidic and one neutral system.
epiderminSupplier
Creative Peptides
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- info@creative-peptides.com
BOC Sciences
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Zhejiang Huida Biotech Co., LTD
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- 0571-89903882 18679456698
- zilong@hizyme.com
Zhejiang Huida Biotech Co., LTD
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- 0571-0571-89903882 15990081639
- sunshixuan@huidabiotech.com