Basic information Safety Supplier Related

ALPHA-DIMETHYLAMINO-3',4'-DIHYDROXYACETOPHENONE HYDROCHLORIDE

Basic information Safety Supplier Related

ALPHA-DIMETHYLAMINO-3',4'-DIHYDROXYACETOPHENONE HYDROCHLORIDE Basic information

Product Name:
ALPHA-DIMETHYLAMINO-3',4'-DIHYDROXYACETOPHENONE HYDROCHLORIDE
Synonyms:
  • 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethanonehydrochloride
  • 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)-ethanonhydrochloride
  • 2-dimethylamino-3’,4’-dihydroxyacetophenonehydrochloride
  • 3’,4’-dihydroxy-2-(dimethylamino)-acetophenonhydrochloride
  • nsc62512
  • ski28467
  • u24274a
  • ALPHA-DIMETHYLAMINO-3',4'-DIHYDROXYACETOPHENONE HYDROCHLORIDE
CAS:
16899-83-5
MF:
C10H14ClNO3
MW:
231.68
EINECS:
207-716-4
Mol File:
16899-83-5.mol
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ALPHA-DIMETHYLAMINO-3',4'-DIHYDROXYACETOPHENONE HYDROCHLORIDE Chemical Properties

Melting point:
236-237 °C
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Safety Information

Safety Statements 
24/25
HS Code 
29225000

MSDS

  • Language:English Provider:ACROS
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ALPHA-DIMETHYLAMINO-3',4'-DIHYDROXYACETOPHENONE HYDROCHLORIDE Usage And Synthesis

Chemical Properties

LIGHT GREY POWDER

Uses

N-Methyladrenalone Hydrochloride-D3 is an intermediate in the synthesis of rac N-Methyl Epinephrine-d6 Hydrochloride (>90%) (M304302) which is the N-methylated analogue of the sympathomimetic hormone Epinephrine (E588585). Recent studies suggest that N-Methylepinephrine may be synthesized from Epinephrine by phenylethanolamine N-methyltransferase present in the brain.

Preparation

Preparation by reaction of the corresponding base (SM) with hydrogen chloride in ethanol. SM was obtained by reaction of 3,4-dihydroxy-a-chloroacetophenone with concentrated aqueous dimethylamine.

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