1-BENZYLPYRROLE Chemical Properties

Melting point:

15 °C

Boiling point:

90 °C0.9 mm Hg(lit.)

Density 

1.03

refractive index 

n20/D 1.5685(lit.)

Flash point:

115 °F

form 

Liquid

pka

-2.90±0.70(Predicted)

color 

Colorless to brown

CAS DataBase Reference

2051-97-0(CAS DataBase Reference)

EPA Substance Registry System

1H-Pyrrole, 1-(phenylmethyl)- (2051-97-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

26-36

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

2933998090

MSDS

• Language:English Provider:SigmaAldrich

1-BENZYLPYRROLE Usage And Synthesis

Chemical Properties

White transparent liquid

Uses

N-benzylpyrrole may be used in the synthesis of the following:

• (E,Z)-3-(7,8-dimethoxy-5H-pyrrolo[2,1-a]isoindol-3-yl)-N,N-diethylacrylamide
• (E,Z)-7,8-dimethoxy-3-styryl-5H-pyrrolo[2,1-a]isoindole
• pyrroloisoquinolines
• (Z)-2-(7,8-dimethoxypyrrolo[1,2-b]isoquinolin-10-ylidene)-N,N-diethylacetamide
• (E,Z)-10-benzylidene-7,8-dimethoxy-5,10-dihydropyrrolo- [1,2-b]isoquinoline
• (E,Z)-7,8-dimethoxy-10-(2-methoxyvinyl)-5,10-dihydropyrrolo[1,2-b]isoquinoline
• (Z)-7,8-dimethoxy-10-(methoxymethylene)-5,10-dihydropyrrolo[1,2-b]isoquinoline
• 2-cyano-N-benzylpyrroles
• 3-cyano-N-benzylpyrroles

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 31, p. 1715, 1994 DOI: 10.1002/jhet.5570310674
Synthetic Communications, 25, p. 1857, 1995 DOI: 10.1080/00397919508015431
Synthesis, p. 457, 1996 DOI: 10.1055/s-1996-4247

General Description

N-benzylpyrrole can be synthesized from N-benzylpyrrolidine via oxidation with 2-iodoxybenzoic acid(IBX) in presence of β-cyclodextrin in aqueous medium.

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