RM 06
RM 06 Basic information
- Product Name:
- RM 06
- Synonyms:
-
- RM 06
- N-[[5-(6-Hydroxy-9H-purin-9-yl)pentyloxy]carbonyl]-L-Leu-L-Met-OH
- N-[[5-[(1,6-Dihydro-6-oxo-9H-purin)-9-yl]pentyloxy]carbonyl]-L-Leu-L-Met-OH
- (2R)-2-[[(2S)-4-methyl-2-[5-(6-oxo-3H-purin-9-yl)pentoxycarbonylamino]pentanoyl]amino]-3-methylsulfanylpropanoic acid
- CAS:
- 126869-52-1
- MF:
- C21H32N6O6S
- MW:
- 496.58038
- Mol File:
- 126869-52-1.mol
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RM 06 Usage And Synthesis
Description
RM 06 is an immunomodulatory agent with a peptidyl-hypoxanthine structure.
Uses
RM 06 is an immunomodulator with a peptidyl hypoxanthine structure that significantly reduces the number of lung metastases of B16 melanoma cells in mice after lethal irradiation and bone marrow reconstitution by stimulating the activity of natural killer (NK) cells[1].
Definition
ChEBI: Omega-(Hypoxanthin-9-yl)-pentoxycarbonyl-leucyl-methionine is a dipeptide.
References
[1] Montaldo, et al. High-performance liquid chromatographic determination in human plasma of a new immunomodulatory agent with a peptidyl-hypoxanthine structure (RM 06). Journal of Chromatography B: Biomedical Sciences and Applications 525 (1990): 471-477. DOI:10.1016/s0378-4347(00)83426-x