bequinostatin C
bequinostatin C Basic information
- Product Name:
- bequinostatin C
- Synonyms:
-
- bequinostatin C
- Benzo[a]naphthacene-2-carboxylic acid, 8,13-dihydro-1,7,9,11-tetrahydroxy-8,13-dioxo-3-pentyl-
- 8,13-Dihydro-1,7,9,11-Tetrahydroxy-8,13-Dioxo-3-Pentylbenzo(a)Naphthacene-2-Carboxylic Acid
- CAS:
- 152175-74-1
- MF:
- C28H22O8
- MW:
- 486.47
- Mol File:
- 152175-74-1.mol
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bequinostatin C Chemical Properties
- Boiling point:
- 794.4±60.0 °C(Predicted)
- Density
- 1.540±0.06 g/cm3(Predicted)
- solubility
- DMSO: Slightly soluble; Methanol: Slightly soluble
- form
- A solid
- pka
- 2.76±0.20(Predicted)
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bequinostatin C Usage And Synthesis
Description
Bequinostatin C is a naphthoquinone originally isolated from Streptomyces and a glutathione S-transferase pi 1 (GSTP1) inhibitor (IC50 = 40 μg/ml for human GSTP1).1
References
1. Yamazaki, T., Tatee, T., Aoyama, T., et al. Bequinostatins C and D, new inhibitors of glutathione S-