4'-PIPERIDINOACETOPHENONE Chemical Properties

Melting point:

85-87 °C (lit.)

Boiling point:

341.6°C (rough estimate)

Density 

1.0156 (rough estimate)

refractive index 

1.5400 (estimate)

storage temp. 

2-8°C

pka

3.59±0.20(Predicted)

CAS DataBase Reference

10342-85-5(CAS DataBase Reference)

EPA Substance Registry System

4'-Piperidinoacetophenone (10342-85-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

4'-PIPERIDINOACETOPHENONE Usage And Synthesis

Chemical Properties

yellow flakes

Uses

Pharmacological activity:

• Selective antimycobacterial activity
• Bronchodilator compound
• Modulation of flagellar motility in Chlamydomonas

General Description

4′-Piperidinoacetophenone undergoes Claisen-Schmidt condensation with substituted benzaldehydes using NaOH-Al₂O₃ by microwave irradiation to give chalcones. It has antimycobacterial activity.

4'-PIPERIDINOACETOPHENONE(10342-85-5)Related Product Information

• Nadifloxacin
• Ipodate Sodium
• 4'-PIPERIDINOACETOPHENONE
• 1-(4-ACETYLPHENYL)-4-PIPERIDINECARBOXYLIC ACID
• ETHYL 1-(4-ACETYL-2-NITROPHENYL)-4-PIPERIDINECARBOXYLATE
• 1-(3-NITRO-4-PIPERIDINOPHENYL)-1-ETHANONE
• 1-(3-AMINO-4-PIPERIDINOPHENYL)-1-ETHANONE
• 1-[4-(4-hydroxypiperidin-1-yl)phenyl]ethan-1-one
• 1-[4-(4-BENZOYLPIPERIDINO)-3-NITROPHENYL]-3-(2-THIENYL)PROP-2-EN-1-ONE
• 1-(4-ACETYL-PHENYL)-PIPERIDINE-4-CARBOXYLIC ACID AMIDE
• 1-(4-(4-[5-(4-CHLOROPHENYL)-1H-PYRAZOL-3-YL]PIPERIDINO)-3-NITROPHENYL)-1-ETHANONE
• 1-(3-NITRO-4-(4-[5-(2-THIENYL)-1H-PYRAZOL-3-YL]PIPERIDINO)PHENYL)-1-ETHANONE
• 1-(4-(4-[5-(4-METHOXYPHENYL)-1H-PYRAZOL-3-YL]PIPERIDINO)-3-NITROPHENYL)-1-ETHANONE
• 1-[3-fluoro-4-(4-methylpiperidin-1-yl)phenyl]ethan-1-one
• 1-[3-fluoro-4-(2-methylpiperidin-1-yl)phenyl]ethan-1-one
• 1-[4-(4-([4-(4-METHOXYPHENYL)PIPERAZINO]CARBONYL)PIPERIDINO)PHENYL]-1-ETHANONE
• 1-(3-FLUORO-4-PIPERIDIN-1-YLPHENYL)ETHANONE
• 1-(4-(4-[5-(2,4-DICHLOROPHENYL)-1H-PYRAZOL-3-YL]PIPERIDINO)-3-NITROPHENYL)-1-ETHANONE