IMISOPASEM MANGANESE
IMISOPASEM MANGANESE Basic information
- Product Name:
- IMISOPASEM MANGANESE
- Synonyms:
-
- IMISOPASEM MANGANESE
- M-40403
- Imisopasem manganese(m40403)
- CG 4419
- CG4419
- CG-4419
- M40403; M 40403; M-40403; CG4419; CG 4419; CG-4419; SC72325; SC-72325; SC 72325; IMISOPASEM MANGANESE
- SC 72325
- CAS:
- 218791-21-0
- MF:
- C21H35N5.Cl2Mn
- MW:
- 483.387
- Mol File:
- 218791-21-0.mol
IMISOPASEM MANGANESE Chemical Properties
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO:5.0(Max Conc. mg/mL);10.34(Max Conc. mM)
DMF:3.0(Max Conc. mg/mL);6.21(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);41.38(Max Conc. mM)
PBS (pH 7.2):3.0(Max Conc. mg/mL);6.21(Max Conc. mM)
Water:16.0(Max Conc. mg/mL);33.1(Max Conc. mM) - form
- A crystalline solid
- color
- White to off-white
IMISOPASEM MANGANESE Usage And Synthesis
Uses
Relief of pain and inflammation.
in vivo
Imisopasem manganese is a small-molecule superoxide dismutase mimetic that has shown efficacy in animal model disease states in which superoxide anions are thought to play a key role. Imisopasem manganese inhibits the inflammatory response following the intrapleural injection of carrageenan in rats. All parameters of inflammation are attenuated by Imisopasem manganese except for NOx, PGE2 and IL-10 which remains unaltered[1]. Decreased apoptosis of the large and particularly the small bowel and marked recovery of both lymphoid and hematopoietic tissues occurs in the Imisopasem manganese pre-treated mice. Imisopasem manganese is effective in reducing TBI-induced tissue destruction and has potential as a new radioprotective agent[2].
IMISOPASEM MANGANESESupplier
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