ETHYL 2-NITROPROPIONATE Chemical Properties

Boiling point:

75-76 °C/9 mmHg (lit.)

Density 

1.13 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.421(lit.)

Flash point:

193 °F

pka

5.98±0.10(Predicted)

Water Solubility 

Not miscible in water.

BRN 

774734

EPA Substance Registry System

Propanoic acid, 2-nitro-, ethyl ester (2531-80-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

RIDADR 

NA 1993 / PGIII

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

ETHYL 2-NITROPROPIONATE Usage And Synthesis

Uses

Ethyl 2-nitropropionate is used in the preparation of (-)-trans-2,5-dimethylprolineethyl ester via enantioselective Michael reaction methyl vinyl ketone using modified dihydroquinine as catalyst, novel nitrogen-15-labeled nitrone spin trap, 5-ethoxycarbonyl-5-methyl-1-pyrroline N-oxide ([15N]EMPO) for detecting superoxide anion, 2-ethoxycarbonyl-2-nitropentanal. It is used for enantioselective Michael reactions.

Uses

Ethyl 2-nitropropionate was used in the preparation of:

• (?)-trans-2,5-dimethylprolineethyl ester via enantioselective Michael reaction methyl vinyl ketone using modified dihydroquinine as catalyst
• novel nitrogen-15-labeled nitrone spin trap, 5-ethoxycarbonyl-5-methyl-1-pyrroline N-oxide ([¹⁵N]EMPO) for detecting superoxide anion
• 2-ethoxycarbonyl-2-nitropentanal

General Description

Ethyl 2-nitropropionate is a nitro ester.

ETHYL 2-NITROPROPIONATE(2531-80-8)Related Product Information

• CBI-BB ZERO/001250
• AKOS BB-9225
• ETHYL 2-NITROBUTYRATE
• AURORA KA-5313
• ETHYL 2-NITROPROPIONATE
• SALOR-INT L160695-1EA
• Diethyl nitromalonate