Z-ALA-PRO-PHE-CHLOROMETHYLKETONE
Z-ALA-PRO-PHE-CHLOROMETHYLKETONE Basic information
- Product Name:
- Z-ALA-PRO-PHE-CHLOROMETHYLKETONE
- Synonyms:
-
- Z-ALA-PRO-PHE-CHLOROMETHYLKETONE
- Z-ALA-PRO-PHE-CMK
- L-Prolinamide, N-[(phenylmethoxy)carbonyl]-L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]- (9CI)
- CAS:
- 217658-18-9
- MF:
- C26H30ClN3O5
- MW:
- 499.99
- Mol File:
- Mol File
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Z-ALA-PRO-PHE-CHLOROMETHYLKETONE Chemical Properties
- storage temp.
- -15°C
- Sequence
- Z-Ala-Pro-Phe-{Chloromethylketone}
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Z-ALA-PRO-PHE-CHLOROMETHYLKETONE Usage And Synthesis
Uses
Z-APF-CMK is a specific inhibitor of Ca2+-regulated nuclear scaffold protease (CRNSP)[1].
References
[1] Zhang D, et al. Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis. Proc Natl Acad Sci U S A. 2001 May 8;98(10):5746-51. DOI:10.1073/pnas.101329598
Z-ALA-PRO-PHE-CHLOROMETHYLKETONESupplier
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