trans-Tranilast Chemical Properties

Melting point:

184 °C(Solv: water (7732-18-5); acetone (67-64-1))

Boiling point:

585.6±50.0 °C(Predicted)

Density 

1.299±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO: 100 mg/mL (305.50 mM)

pka

3.45±0.36(Predicted)

form 

Solid

color 

White to off-white

trans-Tranilast Usage And Synthesis

Uses

Antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.

Uses

trans-Tranilast is used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.

Definition

ChEBI: Tranilast is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group. It has a role as an anti-asthmatic drug, a nephroprotective agent, an anti-allergic agent, a calcium channel blocker, an antineoplastic agent, an aryl hydrocarbon receptor agonist and a hepatoprotective agent. It is a member of cinnamamides, a dimethoxybenzene, an amidobenzoic acid and a secondary carboxamide. It is functionally related to an anthranilic acid.

trans-Tranilast(70806-55-2)Related Product Information

• cis-Tranilast
• 4-Demethyl Tranilast
• Methyl anthranilate
• Tranilast