1-(3-CHLOROPHENYL)-5-TRIFLUOROMETHYL-3-HYDROBENZIMIDAZOL-2-ONE
1-(3-CHLOROPHENYL)-5-TRIFLUOROMETHYL-3-HYDROBENZIMIDAZOL-2-ONE Basic information
- Product Name:
- 1-(3-CHLOROPHENYL)-5-TRIFLUOROMETHYL-3-HYDROBENZIMIDAZOL-2-ONE
- Synonyms:
-
- 1-(3-CHLOROPHENYL)-5-TRIFLUOROMETHYL-3-HYDROBENZIMIDAZOL-2-ONE
- 2H-BENZIMIDAZOL-2-ONE, 1-(3-CHLOROPHENYL)-1,3-DIHYDRO-5-(TRIFLUOROMETHYL)-
- UCCF 853
- UCCF853
- UCCF-853
- UCCF853,UCCF 853
- 1-(3-Chlorophenyl)-5-(trifluoromethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
- T29041
- CAS:
- 625458-06-2
- MF:
- C14H8ClF3N2O
- MW:
- 312.67
- Mol File:
- 625458-06-2.mol
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1-(3-CHLOROPHENYL)-5-TRIFLUOROMETHYL-3-HYDROBENZIMIDAZOL-2-ONE Chemical Properties
- form
- Solid
- color
- White to off-white
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1-(3-CHLOROPHENYL)-5-TRIFLUOROMETHYL-3-HYDROBENZIMIDAZOL-2-ONE Usage And Synthesis
Description
UCCF-853 is an activator of the CFTR Cl- channel which may be useful for therapy of cystic fibrosis.
Uses
UCCF-853 is a CFTR modulator[1].
References
[1] Nicoletta Pedemonte, et al. Influence of cell background on pharmacological rescue of mutant CFTR. Am J Physiol Cell Physiol. 2010 Apr;298(4):C866-74. DOI:10.1152/ajpcell.00404.2009
1-(3-CHLOROPHENYL)-5-TRIFLUOROMETHYL-3-HYDROBENZIMIDAZOL-2-ONESupplier
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