7-BROMO-5-CHLOROINDOLE Chemical Properties

Boiling point:

348.1±22.0 °C(Predicted)

Density 

1.772±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

14.42±0.30(Predicted)

Appearance

Off-white to light yellow Solid

7-BROMO-5-CHLOROINDOLE Usage And Synthesis

Uses

7-Bromo-5-chloroindole is an indole derivative that can be used as a pharmaceutical intermediate.

Synthesis

7-Bromo-5-chloro-1H-indole is synthesized by ring closure reduction of 1-(2-Amino-3-bromo-5-chloro-phenyl.

References

[1] Patent: KR101601357, 2016, B1. Location in patent: Paragraph 0345-0347
[2] Bioorganic and Medicinal Chemistry Letters, 2000, vol. 10, # 11, p. 1223 - 1226

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