2H-BENZO[A]QUINOLIZIN-2-ONE, 1,3,4,6,7,11B-HEXAHYDRO-9,10-DIMETHOXY-3-(2-METHYLPROPYL)-, (3S,11BS)- Chemical Properties

Melting point:

109-115°C

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

Dichloromethane (Slightly), Chloroform (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Off-White

2H-BENZO[A]QUINOLIZIN-2-ONE, 1,3,4,6,7,11B-HEXAHYDRO-9,10-DIMETHOXY-3-(2-METHYLPROPYL)-, (3S,11BS)- Usage And Synthesis

Uses

(-)-Tetrabenazine is a potent inhibitors of vascular monoamine transporter 2 (VMAT2) and may be applicable towards the treatment of chorea associated with Huntington’s disease.

Definition

ChEBI: A 9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one in which both stereocentres have S configuration.

2H-BENZO[A]QUINOLIZIN-2-ONE, 1,3,4,6,7,11B-HEXAHYDRO-9,10-DIMETHOXY-3-(2-METHYLPROPYL)-, (3S,11BS)-(1026016-84-1)Related Product Information

• (S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methyl-2-propylisoquinoline
• 3-METHYL-1-(2-PHENYL)ETHYL-4-PIPERIDINONE
• Tetrabenazine
• 2H-BENZO[A]QUINOLIZIN-2-ONE, 1,3,4,6,7,11B-HEXAHYDRO-9,10-DIMETHOXY-3-(2-METHYLPROPYL)-, (3S,11BS)-