3-Chloro-6-hydrazinopyridazine Chemical Properties

Melting point:

137-141 °C (lit.)

Boiling point:

271.0±23.0 °C(Predicted)

Density 

1.63±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

form 

powder

pka

5.34±0.20(Predicted)

color 

Off-white

BRN 

125591

InChI

InChI=1S/C4H5ClN4/c5-3-1-2-4(7-6)9-8-3/h1-2H,6H2,(H,7,9)

InChIKey

FXYQRYGWWZKUFV-UHFFFAOYSA-N

SMILES

C1(Cl)=NN=C(NN)C=C1

CAS DataBase Reference

17284-97-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-41-43

Safety Statements 

37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2928009090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-Chloro-6-hydrazinopyridazine Usage And Synthesis

Uses

3-Chloro-6-Hydrazinopyridazine (cas# 17284-97-8) is a useful research chemical.

Synthesis

General procedure for the synthesis of 3-chloro-6-hydrazinopyridazine from 3,6-dichloropyridazine: 3,6-dichloropyridazine (3 g, 20.14 mmol) was reacted with hydrazine monohydrate (1 g, 20.14 mmol) in a sealed tube at 80 °C for 5 hours. After completion of the reaction, the solvent was removed by evaporation and the resulting crude product was used directly in the next step of the reaction without further purification (Yield: 3.56 g, Yield: 100%). The product [MH]+ was analyzed by liquid chromatography-mass spectrometry (LCMS, Method B) with m/z of 145.1 and retention time (tR) of 0.57 min.

References

[1] Patent: WO2011/18454, 2011, A1. Location in patent: Page/Page column 62-63
[2] Patent: WO2011/20861, 2011, A1. Location in patent: Page/Page column 67
[3] MedChemComm, 2014, vol. 5, # 4, p. 540 - 546
[4] Bulletin of the Korean Chemical Society, 2018, vol. 39, # 7, p. 853 - 857
[5] Patent: KR2018/94194, 2018, A. Location in patent: Paragraph 0221; 0222; 0223; 0224

3-Chloro-6-hydrazinopyridazine(17284-97-8)Related Product Information

• Sulfachloropyridazine sodium
• Thioridazine
• Pyridaphenthion
• HYDRAZINE
• Ophthazin
• Dihydralazine sulphate
• Hydralazine
• 3-Chloro-6-methylpyridazine
• 3-CHLORO-6-ETHOXYPYRIDAZINE
• 3-chloro-6-(chloroMethyl)pyridazine hydrochloride
• 3-Chloro-6-trifluoromethyl-pyridazine
• 3-Chloro-6-chloromethylpyridazine
• 3-chloro-6-isopropylpyridazine
• 3-CHLORO-6-PROPYLOXYPYRIDAZINE
• 3-CHLORO-6-ISOPROPOXYPYRIDAZINE
• 3-Chloro-6-(1H-pyrazol-1-yl)pyridazine
• 6-Chloro-N-ethylpyridazin-3-amine
• 6-chloro-N-(propan-2-yl)pyridazin-3-amine