L-CARNITINE:HCL, O-OCTANOYL
L-CARNITINE:HCL, O-OCTANOYL Basic information
- Product Name:
- L-CARNITINE:HCL, O-OCTANOYL
- Synonyms:
-
- L-CARNITINE:HCL, O-OCTANOYL
- (R)-3-carboxy-N,N,N-trimethyl-2-(octanoyloxy)propan-1-ammonium chloride
- L-Octanoylcarnitine hydrochloride
- Octanoyl-L-carnitine chloride (L-Octanoylcarnitine chloride)
- (R)-3-(octanoyloxy)-4-(trimethylammonio)butanoate hydrochloride
- (R)-3-Carboxy-N,N,N-trimethyl-2-(octanoyloxy)propan-1-aminium chloride
- CAS:
- 54377-02-5
- MF:
- C15H30ClNO4
- MW:
- 323.856
- Mol File:
- 54377-02-5.mol
L-CARNITINE:HCL, O-OCTANOYL Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMF: 20 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml
- form
- A crystalline solid
- color
- White to off-white
- Appearance
- white solid
L-CARNITINE:HCL, O-OCTANOYL Usage And Synthesis
Description
Octanoylcarnitine, like other acylcarnitines, is an important intermediate in lipid metabolism, necessary for the transport of fatty acids into mitochondria for β-oxidation and ATP production, as well as for the removal of excess short-chain fatty acids. The level of octanoylcarnitine in biological fluids is a diagnostic sign of fatty acid metabolism disorders.
The product is used primarily as a control for MS/MS.
Octanoylcarnitine chloride interferes with the activity of acetyl-CoA carboxylase, an enzyme that catalyzes the conversion of acetyl-CoA to malonyl-CoA. This transformation is a key regulatory step in the process of fatty acid oxidation.
Uses
Octanoyl L-Carnitine Chloride is a metabolite of Carnitine (C184110, L-Carnitine).
in vivo
L-Octanoylcarnitine hydrochloride decreases mucosal and detrusor force-flow respiration and respiratory conductance in male high fat diet (HFD) mice[2].
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