7,8,9,10-Tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine 1,4-Dioxide Chemical Properties

Melting point:

>81°C (dec.)

Boiling point:

524.1±60.0 °C(Predicted)

Density 

1.63±0.1 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly, Sonicated)

form 

Solid

pka

8.99±0.20(Predicted)

color 

Yellow to Beige

7,8,9,10-Tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine 1,4-Dioxide Usage And Synthesis

Uses

7,8,9,10-Tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine 1,4-Dioxide, is an impurity of Varenicline (V098490), a nicotinic α4β2 acetylcholine receptor partial agonist. Aid in smoking cessation.

7,8,9,10-Tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine 1,4-Dioxide(1337563-47-9)Related Product Information

• Varenicline Impurity 3
• Varenicline Impurity 8
• Varenicline Impurity 15
• Ethanone, 2,2,2-trifluoro-1-(1,2,4,5-tetrahydro-7-hydroxy-1,5-methano-3H-3-benzazepin-3-yl)-
• Hydroxy Varenicline
• Varenicline Impurity 13 HCl
• N-Formyl Varenicline
• Varenicline N-Glucoside
• Varenicline Carbamoyl β-D-Glucuronide
• 2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine
• 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)
• Varenicline Impurity 5
• 2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine