3-METHYL-5-(TRIFLUOROMETHYL)BENZYL BROMIDE
3-METHYL-5-(TRIFLUOROMETHYL)BENZYL BROMIDE Basic information
- Product Name:
- 3-METHYL-5-(TRIFLUOROMETHYL)BENZYL BROMIDE
- Synonyms:
-
- 3-METHYL-5-(TRIFLUOROMETHYL)BENZYL BROMIDE
- MF:
- C9H8BrF3
- MW:
- 253.06
- Mol File:
- Mol File
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Safety Information
- Hazard Codes
- C
- Hazard Note
- Corrosive
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3-METHYL-5-(TRIFLUOROMETHYL)BENZYL BROMIDE Usage And Synthesis
Uses
A series of novel five-membered urea derivatives as potent NK1 receptor antagonists is described. The effects of substitution of a 4-fluoro group at the phenyl ring and the introduction of an α-methyl group at the benzylic position to improve potency was found. 3,5-Bis(trifluoromethyl)benzyl bromide has been used as derivatization reagent in detection of uracil in DNA by GC and negative chemical ionization mass spectrometry.