5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester
5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester Basic information
- Product Name:
- 5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester
- Synonyms:
-
- 5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester
- methyl 4-(3,4-difluorophenyl)-6-(methoxymethyl)-2-oxo-3-((3-(4-(pyridin-2-yl)piperidin-1-yl)propyl)carbamoyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
- MCHr1 antagonist 1
- MCHR1 antagonist 1,MCHR-1 antagonist 1
- CAS:
- 391610-37-0
- MF:
- C28H33F2N5O5
- MW:
- 557.5889264
- Mol File:
- 391610-37-0.mol
More
Less
5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
More
Less
5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester Usage And Synthesis
Description
MCHr1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.
MCHr1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with Kis of >50000 nM[1].
References
[1]. Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof. US 20030069261 A1
5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl esterSupplier
MedChemexpress LLC
- Tel
- 021-58955995
- sales@medchemexpress.cn
Fan De(Beijing) Biotechnology Co., Ltd.
- Tel
- 15911056312
- liming@bio-fount.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
Labnetwork lnc.
- Tel
- +86-27-50766799 +8618062016861
- contact@labnetwork.com
BOC Sciences
- Tel
- info@bocsci.com