WD2000-012547
WD2000-012547 Basic information
- Product Name:
- WD2000-012547
- Synonyms:
-
- WD2000-012547
- 6H-Pyrrolo[4,3,2-ef][2]benzazepin-6-one, 1,3,4,5-tetrahydro-2-phenyl-
- WD2000 012547,WD2000012547,WD-2000-012547
- CAS:
- 283172-68-9
- MF:
- C17H14N2O
- MW:
- 262.30586
- Mol File:
- 283172-68-9.mol
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WD2000-012547 Chemical Properties
- Melting point:
- 249-255 °C (decomp)
- Boiling point:
- 600.2±44.0 °C(Predicted)
- Density
- 1.270±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 14.94±0.20(Predicted)
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WD2000-012547 Usage And Synthesis
Uses
WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pKi of 8.221.
IC 50
PARP-1: 8.221 (pKi)
References
[1] Fatima S, et al. Multiple receptor conformation docking, dock pose clustering and 3D QSAR studies on human poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. J Recept Signal Transduct Res. 2014 Oct;34(5):417-30. DOI:10.3109/10799893.2014.917323
WD2000-012547Supplier
MedChemexpress LLC
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