Naldemedine
Naldemedine Basic information
- Product Name:
- Naldemedine
- Synonyms:
-
- Naldemedine
- (5α)-3-(Acetyloxy)-17-(cyclopropylmethyl)-4,5-epoxy-14-[[[[1-methyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl]amino]carbonyl]oxy]-morphinan-6-one
- Morphinan-6-one, 3-(acetyloxy)-17-(cyclopropylmethyl)-4,5-epoxy-14-[[[[1-methyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl]amino]carbonyl]oxy]-, (5α)-
- CAS:
- 1374774-70-5
- MF:
- C34H36N4O7
- MW:
- 612.67
- Mol File:
- 1374774-70-5.mol
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Naldemedine Chemical Properties
- Density
- 1.42±0.1 g/cm3(Predicted)
- pka
- 8.95±0.46(Predicted)
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Naldemedine Usage And Synthesis
Uses
(5α)-3-(Acetyloxy)-17-(cyclopropylmethyl)-4,5-epoxy-14-[[[[1-methyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl]amino]carbonyl]oxy]-morphinan-6-one is an intermediate used in the synthesis of Naldemedine (N232550), which is a peripherally selective mu opioid receptor antagonist used in the treatment in pain.
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