Benserazide Hydrochloride impurity C
Benserazide Hydrochloride impurity C Basic information
- Product Name:
- Benserazide Hydrochloride impurity C
- Synonyms:
-
- Benserazide Hydrochloride impurity C
- Benserazide EP Impurity C HCl
- CSRM617 hydrochloride (CSRM-617)
- (2,3,4-Trihydroxyphenyl)methylene]hydrazide-serine Hydrochloride
- 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzylidene)propanehydrazide hydrochloride
- Benzylhydrazone hydrochloride
- Benserazide EP Impurity C(Hydrochloride)
- Benserazide P-1
- CAS:
- 1353749-74-2
- MF:
- C10H14ClN3O5
- MW:
- 291.69
- EINECS:
- 940-411-0
- Mol File:
- 1353749-74-2.mol
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Benserazide Hydrochloride impurity C Chemical Properties
- Melting point:
- >177°C (dec.)
- Density
- 1.68g/cm3 at 21℃
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- DMSO (Slightly), Water (Slightly, Sonicated)
- form
- Solid
- color
- Off-White to Pale Beige
- LogP
- 1 at 40℃ and pH6.5
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Benserazide Hydrochloride impurity C Usage And Synthesis
Uses
[(2,3,4-Trihydroxyphenyl)methylene]hydrazide-serine Hydrochloride is an impurity of Benserazide (B120505) which is a drug which in combination with dopamine precursor Levodopa (D533751) is used in the management of Parkinson’s disease.
in vivo
CSRM617 (50 mg/kg; p.o.; daily, for 20 d) inhibits tumor growth in SCID mice with 22Rv1 xenograft[1].
| Animal Model: | SCID mice with 22Rv1 xenograft[1] |
| Dosage: | 50 mg/kg |
| Administration: | Oral administration; daily, for 20 days |
| Result: | Elicited a significant reduction in the onset and growth of diffuse metastases. |
Benserazide Hydrochloride impurity CSupplier
Shanghai EFE Biological Technology Co., Ltd.
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Rhawn Reagent
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TOSUN PHARM
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Shanghai Star Pharmaceutical Chemical Technology Co., Ltd.
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