2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE
2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Basic information
- Product Name:
- 2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE
- Synonyms:
-
- LY 225910
- 2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE
- 2-(2-(5-Bromo-(1H)-indol-3-yl)ethyl)-3-(3-(1-methylethoxy)phenyl)-4-(3H)-quinazoline
- 2-(2-(5-BroMo-1H-indol-3-yl)ethyl)-3-(3-isopropoxyphenyl)quinazolin-4(3H)-one
- 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
- 4(3H)-Quinazolinone, 2-[2-(5-bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy)phenyl]-
- CAS:
- 133040-77-4
- MF:
- C27H24BrN3O2
- MW:
- 502.4
- Mol File:
- 133040-77-4.mol
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2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Chemical Properties
- Flash point:
- 337 - 405℃
- storage temp.
- Desiccate at -20°C
- solubility
- DMSO: >20mg/mL
- form
- powder
- color
- off-white
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2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Usage And Synthesis
Uses
LY 225910 is a potent CCK-BR antagonist.
Definition
ChEBI: 2-[2-(5-bromo-1H-indol-3-yl)ethyl]-3-(3-propan-2-yloxyphenyl)-4-quinazolinone is a member of quinazolines.
Biological Activity
Potent CCK 2 receptor antagonist (IC 50 = 9.3 nM for inhibition of 125 I-labeled CCK-8 sulfate binding at mouse brain membranes).
storage
Desiccate at -20°C
2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONESupplier
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