4'-FLUORO-BIPHENYL-4-CARBOXYLIC ACID Chemical Properties

Melting point:

235-240 °C

Boiling point:

369.4±25.0 °C(Predicted)

Density 

1.261±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

4.14±0.10(Predicted)

color 

White to Off-White

CAS DataBase Reference

5731-10-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,N,Xi

Risk Statements 

22-36/37/38-51/53

Safety Statements 

26-60-61

WGK Germany 

2

HazardClass 

IRRITANT

HS Code 

2916399090

MSDS

• Language:English Provider:SigmaAldrich

4'-FLUORO-BIPHENYL-4-CARBOXYLIC ACID Usage And Synthesis

Uses

4-(4-Fluorophenyl)benzoic acid (Compoud 6) can bind to Bcl-2 with a KD value of 400 μM. 4-(4-Fluorophenyl)benzoic acid can be used to develope Bcl-2 selective anti-cancer agent[1].

References

[1] Petros AM, et al. Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6587-91. DOI:10.1016/j.bmcl.2010.09.033

4'-FLUORO-BIPHENYL-4-CARBOXYLIC ACID(5731-10-2)Related Product Information

• 3',4'-DIFLUORO-BIPHENYL-4-CARBOXYLIC ACID
• 4'-FluoroBiphenyl-4-carBoxylicacidethylester
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• 4'-FLUORO-BIPHENYL-4-CARBOXYLIC ACID
• 2'-FLUORO-BIPHENYL-2-CARBOXYLIC ACID
• 3'-FLUORO-BIPHENYL-2-CARBOXYLIC ACID
• 3'-FLUORO-BIPHENYL-3-CARBOXYLIC ACID
• 4'-FLUORO-BIPHENYL-2-CARBOXYLIC ACID
• 3'-FLUORO-BIPHENYL-4-CARBOXYLIC ACID
• 4&#39-Fluoro-biphenyl-4-carboxylic acid
• 4'-AMINO-3'-FLUORO-BIPHENYL-4-CARBOXYLIC ACID METHYL ESTER
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• METHYL 4'-FLUORO[1,1'-BIPHENYL]-4-CARBOXYLATE
• [1,1'-BIPHENYL]-4-CARBOXYLIC ACID, 3-AMINO-4'-FLUORO-
• 2',3',4',5',6'-PENTAFLUORO[1,1'-BIPHENYL]-4-CARBOXYLIC ACID
• 4'-FLUORO-3'-METHYLBIPHENYL-4-CARBOXYLIC ACID
• 4'-FLUORO-3-METHOXY-BIPHENYL-4-CARBOXYLIC ACID METHYL ESTER
• BUTTPARK 143\40-09