Basic information Safety Supplier Related

CAFFEINE-D3

Basic information Safety Supplier Related

CAFFEINE-D3 Basic information

Product Name:
CAFFEINE-D3
Synonyms:
  • CAFFEINE-D3 (7-METHYL-D3)
  • CAFFEINE-D3
  • Caffeine-d3 (7-methyld-d3)
  • 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-7-(methyl-d3)-
  • Caffeine D3Q: What is Caffeine D3 Q: What is the CAS Number of Caffeine D3 Q: What is the storage condition of Caffeine D3
  • 1,3-dimethyl-7-(methyl-d3)-3,7-dihydro-1H-purine-2,6-dione
  • Caffeine-d3 (Diphenhydramine EP Impurity C-d3, Pentoxifylline EP Impurity F-d3, Theophylline EP Impurity A-d3, Theophylline-Ethylenediamine EP Impurity A-d3)
CAS:
26351-04-2
MF:
C8H10N4O2
MW:
194.19
Mol File:
26351-04-2.mol
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CAFFEINE-D3 Chemical Properties

Melting point:
236 - 238°C
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
Appearance
white powder
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CAFFEINE-D3 Usage And Synthesis

Description

Caffeine-d3 is deuterated caffeine and intended for use as an internal standard for the quantification of caffeine by GC- or LC-MS.


Caffeine is a naturally occurring central nervous system stimulant belonging to the methylxanthine class and is widely recognized as the most utilized psychoactive stimulant worldwide. Caffeine's primary mechanism of action involves its effects on adenosine receptors in the brain. Being both fat- and water-soluble component, caffeine easily crosses the blood-brain barrier and antagonizes all 4 adenosine receptor subtypes (A1, A2a, A2b, and A3). The antagonism of the A2a receptor is particularly responsible for caffeine's wakefulness effects. Caffeine increases renal blood flow, glomerular filtration, and sodium excretion, resulting in diuresis. Additionally, caffeine is a potent stimulator of gastric acid secretion and gastrointestinal motility.

Uses

Caffeine-d3 (7-methyl-d3) is the labeled version of Caffeine (C080100(P)), which is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor.

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