NALOXONE-D5
NALOXONE-D5 Basic information
- Product Name:
- NALOXONE-D5
- Synonyms:
-
- NALOXONE-D5
- 17-Allyl-4,5a-epoxy-3,14-dihydroxymorphinan-6-one-d5 Hydrochloride
- 5a)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl-d5)morphinan-6-one Hydrochloride
- EN-15304-d5
- Nalone-d5
- Narcan-d5
- Narcanti-d5
- 17-Allyl-4,5α-epoxy-3,14-dihydroxyMorphinan-6-one-d5 Hydrochloride
- CAS:
- 1261079-38-2
- MF:
- C19H21NO4
- MW:
- 327.38
- EINECS:
- 200-659-6
- Product Categories:
-
- Isotope Labelled Compounds
- Intermediates & Fine Chemicals
- Isotope Labeled Compounds
- Pharmaceuticals
- Mol File:
- Mol File
NALOXONE-D5 Chemical Properties
- Melting point:
- 200-2050C
- Flash point:
- 9℃
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
Safety Information
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25
- Safety Statements
- 7-16-36/37-45
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
- WGK Germany
- 1
NALOXONE-D5 Usage And Synthesis
Description
Naloxone-d5 (CRM) (Item No. 18274) is a certified reference material intended for use as an internal standard for the quantification of naloxone (Item Nos. ISO60191 | 15594) by GC- or LC-MS. Naloxone is categorized as an opioid antagonist. Formulations containing naloxone have been used as antidotes for opioid overdose and the prevention of overdose. They have also been used in combination with buprenorphine (Item Nos. ISO60178 | 14025) in the treatment of opiate addiction and in pain management. This product is intended for research and forensic applications.
Chemical Properties
NALOXONE-D5 is Crystalline Solid
Uses
Labelled specific opioid antagonist. Narcotic antagonist. Intended for use as an internal standard for the quantification of Naloxone by GC- or LC-mass spectrometry.
References
[1] BERTRAND LE BOURDONNEC . Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as μ opioid receptor antagonists with improved opioid receptor selectivity profiles[J]. Bioorganic & Medicinal Chemistry Letters, 2008, 18 6: Pages 2006-2012. DOI: 10.1016/j.bmcl.2008.01.106
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