D-ALA-GLY-PHE-MET-NH2 ACETATE SALT
D-ALA-GLY-PHE-MET-NH2 ACETATE SALT Basic information
- Product Name:
- D-ALA-GLY-PHE-MET-NH2 ACETATE SALT
- Synonyms:
-
- des-tyr1,(D-ala2)-methionine*enkephalinamide acet
- DES-TYR1,(D-ALA2)-METHIONINE*ENKEPHALINA MIDE ACETAT
- D-ALA-GLY-PHE-MET-NH2 ACETATE SALT
- DES-TYR1,[D-ALA2]-METHIONINE ENKEPHALINAMIDE ACETATE SALT
- d-ala-gly-phe-met-nh2
- (des-tyrosine1,D-alanine2)methionine enkephalinamide
- D-Ala-Gly-Phe-Met-NH2 monoacetate
- CAS:
- 100929-65-5
- MF:
- C21H33N5O6S
- MW:
- 483.58
- Mol File:
- 100929-65-5.mol
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D-ALA-GLY-PHE-MET-NH2 ACETATE SALT Chemical Properties
- storage temp.
- −20°C
MSDS
- Language:English Provider:SigmaAldrich
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D-ALA-GLY-PHE-MET-NH2 ACETATE SALT Usage And Synthesis
Uses
D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, is a potent opiate δ-receptor agonist[1].
in vivo
D-Ala-Gly-Phe-Met-NH2 monoacetate (7.1 nM and 14.2 nM (0.5 μL); microinjection; male Sprague-Dawley rats) increases ethanol intake in preference to food in the nucleus accumbens (NAc)[1].
| Animal Model: | Male Sprague-Dawley rats (200-250 g)[1] |
| Dosage: | 7.1 nM and 14.2 nM (0.5 μL) |
| Administration: | Microinjection in the nucleus accumbens (NAc) |
| Result: | Increased ethanol intake in the nucleus accumbens (NAc). |
References
[1] Barson JR, et, al. Opioids in the nucleus accumbens stimulate ethanol intake. Physiol Behav. 2009 Oct 19;98(4):453-9. DOI:10.1016/j.physbeh.2009.07.012
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