(Triphenylphosphoranylidene)acetonitrile Chemical Properties

Melting point:

189-195 °C (lit.)

Boiling point:

465.3±28.0 °C(Predicted)

Density 

1.16±0.1 g/cm3(Predicted)

Flash point:

>110°C

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

powder to crystal

color 

White to Orange to Green

InChI

InChI=1S/C20H16NP/c21-16-17-22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,17H

InChIKey

APISVOVOJVZIBA-UHFFFAOYSA-N

SMILES

C(#N)C=P(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

UN 2811 6.1/PG III

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

6.1

PackingGroup 

III

HS Code 

29319090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

(Triphenylphosphoranylidene)acetonitrile Usage And Synthesis

Chemical Properties

off-white to light yellow crystalline powder

Uses

(Triphenylphosphoranylidene)acetonitrile is a reactant in the synthesis of largazole analogues which displays potent cell growth inhibition and cytotoxicity. As well, is used in the synthesis of monoterpene derivatives against leukemia.

Acquired resistance

(Triphenylphosphoranylidene)acetonitrile may be generated by deprotonation of the corresponding phosphonium salt, by cyanation of Methylenetriphenylphosphorane with p-tolyl cyanate, or by the reaction of Acrylonitrile with (Methoxycarbonylmethylene)triphenylphosphorane.

reaction suitability

reaction type: C-C Bond Formation

(Triphenylphosphoranylidene)acetonitrile(16640-68-9)Related Product Information

• (Triphenylphosphoranylidene)acetonitrile
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