5'-IODORESINIFERATOXIN
5'-IODORESINIFERATOXIN Basic information
- Product Name:
- 5'-IODORESINIFERATOXIN
- Synonyms:
-
- 5'-IODORESINIFERATOXIN
- 6,7-DEEPOXY-6,7-DIDEHYDRO-5-DEOXY-21-DEPHENYL-21-(PHENYLMETHYL)-DAPHNETOXIN,20-(4-HYDROXY-5-IODO-3-METHOXYBENZENEACETATE)
- I-RTX
- I-RTX, 6,7-Deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)-daphnetoxin,20-(4-hydroxy-5-iodo-3-methoxybenzeneacetate)
- 5'-IRTX >99%
- MF:
- C37H39IO8
- MW:
- 738.61
- Product Categories:
-
- Antagonist
- Mol File:
- Mol File
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5'-IODORESINIFERATOXIN Chemical Properties
- storage temp.
- −20°C
- solubility
- DMSO: 10 mg/mL, soluble
- form
- solid
- color
- white
MSDS
- Language:English Provider:SigmaAldrich
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5'-IODORESINIFERATOXIN Usage And Synthesis
Uses
5’-Iodoresiniferatoxin is a potent vanilloid receptor antagonist. Binds to TRPV1 (VR1) receptors expressed in HEK293 cells.
Biological Activity
Potent and silent vanilloid receptor antagonist, 40-fold more potent than capsazepine . Binds to TRPV1 (VR1) receptors expressed in HEK293 cells with a K i of 5.8 nM.