1-Oleoyl lysophosphatidic acid sodium salt Chemical Properties

storage temp. 

-20°C

form 

solid

color 

white

Water Solubility 

Soluble in water up to 5mg/ml with sonication

Sensitive 

Light & Air Sensitive & Hygroscopic

Safety Information

WGK Germany 

3

MSDS

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1-Oleoyl lysophosphatidic acid sodium salt Usage And Synthesis

Uses

Oleoyl-L-α-lysophosphatidic Acid reduces the organ injury caused by endotoxemia in the rat.?It may be useful in the treatment of shock of various etiologies.

General Description

Lysophosphatidic acid (LPA) is an essential metabolite for membrane biosynthesis. LPA interacts with the G protein-coupled receptors (GPCRs), called the LPA receptor and mediates signaling. Oleoyl-L-α-lysophosphatidic acid activates the receptor LPA4. In keratinocytes, oleoyl-L-α-lysophosphatidic acid promotes growth to some extent.

Biochem/physiol Actions

Endogenous agonist for LPA1 and LPA2 receptors. LPA does not induce angiogenesis, but has effects on endothelial cell physiology that are similar to those of sphingosine 1-phosphate. Induces cell migration of cancer and non-cancer cells.

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• DOPS