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6-(TRIFLUOROMETHYL)URACIL

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6-(TRIFLUOROMETHYL)URACIL Basic information

Product Name:
6-(TRIFLUOROMETHYL)URACIL
Synonyms:
  • 6-(Trifluoromethyl)uracil 98%
  • 6-(TRIFLUOROMETHYL)URACIL
  • 6-(TRIFLUOROMETHYL)URACYL
  • 6-(TRIFLUOROMETHYL)-2,4-(1H,3H)PYRIMIDINEDIONE
  • 2,4(1H,3H)-Pyrimidinedione, 6-(trifluoromethyl)-
  • 6-(Trifluoromethyl)-2,4-pyrimidinediol
  • 6-Trifluoromethyl-1H-pyrimidine-2,4-dione
  • 6-(Trifluoromethyl)pyrimidine-2,4(1H,3H)-dione
CAS:
672-45-7
MF:
C5H3F3N2O2
MW:
180.08
EINECS:
211-593-2
Product Categories:
  • Pyrimidine series
  • Heterocyclic Compounds
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrimidines
Mol File:
672-45-7.mol
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6-(TRIFLUOROMETHYL)URACIL Chemical Properties

Melting point:
230-235 °C (lit.)
Density 
1.554±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
4.70±0.10(Predicted)
form 
Powder
CAS DataBase Reference
672-45-7(CAS DataBase Reference)
NIST Chemistry Reference
Uracil, 6-(trifluoromethyl)-,(672-45-7)
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Safety Information

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29335990

MSDS

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6-(TRIFLUOROMETHYL)URACIL Usage And Synthesis

Uses

6-(Trifluoromethyl)-2,4(1H,3H)-pyrimidinedione is an anticancer drug, produced from catalytic trifluoromethylation of uracil.

Synthesis Reference(s)

The Journal of Organic Chemistry, 24, p. 113, 1959 DOI: 10.1021/jo01083a607

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