2-CYANO-3-HYDROXY-N-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTENAMIDE
2-CYANO-3-HYDROXY-N-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTENAMIDE Basic information
- Product Name:
- 2-CYANO-3-HYDROXY-N-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTENAMIDE
- Synonyms:
-
- 2-CYANO-3-HYDROXY-N-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTENAMIDE
- (2E)-2-cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]but-2-enamide
- 2-Butenamide, 2-cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]-, (E)- (9CI)
- CAS:
- 63927-51-5
- MF:
- C12H9F3N2O2
- MW:
- 270.21
- Mol File:
- Mol File
More
Less
2-CYANO-3-HYDROXY-N-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTENAMIDE Usage And Synthesis
Uses
2-Cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]-2-butenamide is a derivative of Leflunomide(L322750) which is an immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index).This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.
2-CYANO-3-HYDROXY-N-[3-(TRIFLUOROMETHYL)PHENYL]-2-BUTENAMIDESupplier
Key Organics Ltd.
- Tel
- +44 (0) 1840-212137
- info@keyorganics.net
Key Organics Limited/Bionet Research
- Tel
- +44 1840 212171
- enquiries@keyorganics.ltd.uk
Ryan Scientific, Inc.
- Tel
- 843-884-4911 x 319
- ryan.reichlyn@ryansci.com
CARBONE SCIENTIFIC CO.,LTD
- Tel
- +44(0)870 486 8629
- sales@carbonesci.com
3B Scientific Corporation
- Tel
- 847.281.9822
- sales@3bsc.com