A[5']P4[5']A AMMONIUM SALT
A[5']P4[5']A AMMONIUM SALT Basic information
- Product Name:
- A[5']P4[5']A AMMONIUM SALT
- Synonyms:
-
- P1,P4-DI(ADENOSINE-5') TETRAPHOSPHATE AMMONIUM SALT
- 5’-(pentahydrogentetraphosphate)adenosine5’-5’-esterwithadenosinetetraam
- adenosine,5’-(pentahydrogentetraphosphate),5’,5’-esterwithadenosine,tetra
- diadenosine5’,5’’’-p(sup1),p(sup4)-tetraphosphatetetraammoniumsalt
- moniumsalt
- A[5']P4[5']A AMMONIUM SALT
- DIADENOSINE TETRAPHOSPHATE AMMONIUM SALT
- P1,P4-DI(ADENOSINE-5')TETRAPHOSPHATEAMMO NIUM
- CAS:
- 102783-36-8
- MF:
- C20H31N11O19P4
- MW:
- 853.42
- Mol File:
- 102783-36-8.mol
A[5']P4[5']A AMMONIUM SALT Chemical Properties
- storage temp.
- -20°C
- solubility
- H2O: 50 mg/mL
- form
- powder
- color
- white
Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- RTECS
- AU7411600
MSDS
- Language:English Provider:SigmaAldrich
A[5']P4[5']A AMMONIUM SALT Usage And Synthesis
Uses
P1,P4-Di(adenosine-5’) Tetraphosphate Ammonium Salt is a derivative of Diadenosine polyphosphate, which is stored in secretory granules of thrombocytes.
Uses
P1,P4-Di(adenosine-5′) tetraphosphate ammonium salt has been used as a substrate for nudix hydrolyse. It has also been used as a ATP analog and nudix substrate for cleavage factor II Im25 subunit.
Biochem/physiol Actions
Diadenosine polyphosphate (Ap4A) functions as a second messenger in pancreatic cells. Diadenosine polyphosphate is majorly stored in neuronal cells, thrombocytes and chromaffin. It stimulates phospholipase D, fluctuates intracellular calcium levels, induces nitric oxide release, activates 5′-nucleotidase, and inhibits adenosine kinase activity?in vitro. The membrane-bound ectoenzymes in endothelial cells in blood plasma and smooth muscle cell metabolize Ap4A.
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